According to CDC data from 2019, the cancer incidence rate in the US was 450.8 per 100,000 people, while the mortality rate was 146.0 per 100,000 people. Rates vary widely on a state level, however, due to demographic factors, lifestyle choices, healthcare accessibility, racial backgrounds and more.

The highest age-adjusted cancer incidence numbers were found in Kentucky, where, at 516.6 per 100,000 people, the rate was more than 13 percent above the national average. Following closely behind was Iowa at 501.8 and Louisiana at 498.8.

The states with the lowest cancer rates in 2019 were Nevada, at 351.5 per 100,000 people, Arizona at 379.5 and New Mexico at 381.0.

When it comes to cancer mortality rates, Mississippi ranked worst at 146.0 per 100,000 people — that's more than 20 percent above the US average. Kentucky and West Virginia had the second- and third-highest mortality rates, at 176.1 and 173.7, respectively.

Utah was home to the lowest cancer mortality rate in 2019, at 117.8 cases per 100,000, followed by Colorado at 126.0 and Hawaii at 126.7.

Via USAFacts.