Provisional CDC data counted 694,708 heart disease deaths, about 1.6 percent more than in 2024.
Provisional CDC data show 694,708 U.S. deaths with heart disease as the underlying cause in 2025, up about 1.6 percent from 683,491 in 2024. That increase is a raw count, not evidence that the heart disease death rate rose; the report's all-cause age-adjusted mortality rate fell 4.6 percent.
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The number of U.S. deaths with heart disease as the underlying cause increased in 2025, according to provisional federal data. The National Center for Health Statistics report counted 694,708 heart disease deaths, up 11,217, or about 1.6 percent, from the final 2024 count of 683,491. Heart disease remained the country's leading cause of death.
Heart disease deaths are on the rise in the US
The comparison is about the number of death certificates listing heart disease as the underlying cause, not a heart-disease-specific mortality rate. The report separately found that the overall age-adjusted death rate across all causes fell 4.6 percent, from 722.1 to 689.2 deaths per 100,000 people, the lowest U.S. rate on record.
The report did not analyze why the heart disease death count increased, so its figures do not support attributing the change to a particular cause.
The 2025 estimate was based on 99.9 percent of death records received and processed by May 10, 2026. NCHS cautioned that provisional numbers and rates can change as more information arrives, and that December data were less complete because of reporting delays.
The report recorded 3,094,593 deaths from all causes in 2025. Its cause-of-death ranking used the underlying cause listed on death certificates.
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