ScienceGirdin-L linked to the breakdown of primary cilia on cells
Science reports that Girdin-L is an unexpected binding partner for a region of the protein Dishevelled called the PDZ domain.
TLDR
Science reports that proximity labeling and biophysical analysis identified Girdin-L as an unexpected binding partner for Dishevelled’s PDZ domain. The analysis found that Girdin-L plays an important role in promoting the breakdown of primary cilia on cells.
Girdin-L linked to the breakdown of primary cilia on cells
Science reports that Girdin-L is an unexpected binding partner for a region of the protein Dishevelled called the PDZ domain.
TLDR
Science reports that proximity labeling and biophysical analysis identified Girdin-L as an unexpected binding partner for Dishevelled’s PDZ domain. The analysis found that Girdin-L plays an important role in promoting the breakdown of primary cilia on cells.
