Dog DNA methylation patterns offer clues to size-related lifespan differences

Science describes a study using 1,640 methylomes from 894 dogs to develop an epigenetic clock that predicted mortality.

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TLDR

A post points to epigenetics, particularly DNA methylation patterns, as a possible explanation for why small dogs live longer than large ones. The linked Science study describes an epigenetic clock developed using 1,640 methylomes from 894 dogs that predicted mortality. Its title links epigenetic aging and transposon dysregulation to size-related lifespan compression.

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