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South American lungfish reportedly has the largest sequenced animal genome

Science reports that Lepidosiren paradoxa has 91 billion DNA bases—30 times the human genome—but roughly the same number of genes.

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TLDR

Science reports that researchers in 2024 put the South American lungfish’s genome at 91 billion DNA bases, the largest sequenced in an animal so far. It has roughly 20,000 genes, about as many as humans, while much of the rest is noncoding DNA that may be “junk.” By comparing lungfish genomes, researchers determined that the species adds the equivalent of a human genome to its DNA every 10 million years.

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Combined views

20K

1 Source, first seen 1h ago

153 likes8 comments28 saves19 reposts
This odd fish has 30 times as much DNA as humans—a new record for animals

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@ScienceMagazineA species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. The DNA of Lepidosiren paradoxa comprises a staggering 91 billion chemical letters or “bases,” 30 times as many as the human genome, researchers reported in 2024. However, those 91 billion bases of DNA only contain about the same number of genes that humans have—roughly 20,000—with the rest consisting of noncoding, perhaps even “junk” DNA. By comparing this genome with those of other lungfishes, the researchers determined that L. paradoxa adds the equivalent of a human genome to its DNA every 10 million years. Learn more on #WorldAnimalDay: https://scim.ag/4o4YCe51h
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    @ScienceMagazineA species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far. The DNA of Lepidosiren paradoxa comprises a staggering 91 billion chemical letters or “bases,” 30 times as many as the human genome, researchers reported in 2024. However, those 91 billion bases of DNA only contain about the same number of genes that humans have—roughly 20,000—with the rest consisting of noncoding, perhaps even “junk” DNA. By comparing this genome with those of other lungfishes, the researchers determined that L. paradoxa adds the equivalent of a human genome to its DNA every 10 million years. Learn more on #WorldAnimalDay: https://scim.ag/4o4YCe51h
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