The research focuses on genetic variants within gut bacteria, beyond the species and metabolites often discussed in connection with health.
A microbiome-wide research paper links single-nucleotide variants in gut microbes to health and exposures. A commentator notes that bacterial genetic variants, alongside microbial species and their metabolites, relate to disease and health.
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@EricTopolIt's not just species of the gut microbiome, or their metabolites, but also genomic variants in the bacteria, that relate to diseases and health https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6
@BagaiDrMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. 940 independent associations across 69 host factors, age, sex cardiovascular and metabolic parameters. Structural analyses host-phenotype-associated SNVs in https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6
@gglinskiiMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@EricTopolIt's not just species of the gut microbiome, or their metabolites, but also genomic variants in the bacteria, that relate to diseases and health https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@BagaiDrMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. 940 independent associations across 69 host factors, age, sex cardiovascular and metabolic parameters. Structural analyses host-phenotype-associated SNVs in https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@gglinskiiMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@EricTopolIt's not just species of the gut microbiome, or their metabolites, but also genomic variants in the bacteria, that relate to diseases and health https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@BagaiDrMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. 940 independent associations across 69 host factors, age, sex cardiovascular and metabolic parameters. Structural analyses host-phenotype-associated SNVs in https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@gglinskiiMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@EricTopolIt's not just species of the gut microbiome, or their metabolites, but also genomic variants in the bacteria, that relate to diseases and health https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@BagaiDrMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. 940 independent associations across 69 host factors, age, sex cardiovascular and metabolic parameters. Structural analyses host-phenotype-associated SNVs in https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6@gglinskiiMicrobiome-wide PheWAS links gut microbial SNVs to health and exposures. https://www.nature.com/articles/s41586-026-11220-0?error=cookies_not_supported&code=a5d03154-1ecf-4aef-a9fa-b1991b4ac7e6
