Report

RGS4 helps sustain chronic pain-related hypersensitivity in mice

Science Signaling reports that deleting Rgs4 in certain mouse sensory nerve fibers reduced hypersensitivity without affecting acute pain responses.

1 Source, 20d ago, first seen 20d ago

An abstract image composed of various colors, including red, green, blue, and white, forming a textured, organic pattern resembling a microscopic view. The colors appear as clusters with an irregular distribution across a dark background.

TLDR

Science Signaling reports that RGS4 in the dorsal root ganglia helps maintain chronic pain-related hypersensitivity in mice. Deleting Rgs4 in certain sensory nerve fibers reduced hypersensitivity without affecting acute pain responses. The findings may inform the development of precision drugs targeting pain-related GPCR signaling.

Today's Rank

—

Not ranked yet

Combined views

22.1K

1 Source, first seen 20d ago