Anshul Kundaje#1675
Binder design has come of age thanks to generative models—but how can we access the wider array of dynamic, multistate protein functions, so elegantly employed by nature?
@mihirbafna14 and I are excited to share SwitchCraft, a framework for designing such functions. (1/7)
Big thanks to co-authors @mihirbafna14 , Anisha Parsan, @HeyuanMNi , David Kwabi-Addo, Bryan Bryson, Adam Klivans, and @lab_berger . We will be presenting at ICML 2026.
Wet lab results on the way!
Preprint: https://arxiv.org/abs/2605.31236 Code: https://github.com/bjing2016/switchcraft (7/7)
Anshul Kundaje#1675Binder design has come of age thanks to generative models—but how can we access the wider array of dynamic, multistate protein functions, so elegantly employed by nature?
@mihirbafna14 and I are excited to share SwitchCraft, a framework for designing such functions. (1/7)
Users praised the SwitchCraft Framework for designing dynamic multistate protein functions, calling the work really cool and offering congratulations to the researchers.