/Tech4h ago

AI Chatbot Blocks Query On Generative Protein And Enzyme Design

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Original post
elvis@omarsar0#510inTech

This is ridiculous and sad.

So, not even deep research reports on biology topics are allowed.

Ugh!!!

8:17 AM · Jun 10, 2026 · 6.5K Views
Sentiment

Many users criticized the AI chatbot for blocking queries on generative protein and enzyme design, calling the restrictions dystopian, cult-like, and exhausting for researchers.

Pos
16.7%
Neg
83.3%
7 comments with sentiment.
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elvis@omarsar0

It doesn't feel like it. And which scientists exactly? Because most of the great scientists using AI that I know are already frustrated with those guardrails you all put in place.

elvis@omarsar0

This is ridiculous and sad.

So, not even deep research reports on biology topics are allowed.

Ugh!!!

4hViews 1.2KLikes 9Bookmarks 1
Bing Xu@bingxu_

@omarsar0 We have better choice.

3hViews 32Likes 1
Dan Greller@dgreller

@omarsar0 Do we not think this will be resolved with tuning? In the meantime, you can use 4.8 for those tasks.

4hViews 50
Mariusz Kurman@mkurman88

@omarsar0 I saw much more absurd, like a simple “hi” forwarded 😄

4hViews 47
elvis@omarsar0

@bingxu_ I switched most of my workflows to GPT-5.5 already, so we are all good. :)

3hViews 12
Rugbist@rugbist_

@omarsar0 flagging biology as unsafe feels dystopian but also predictable at this point

4h
Invincible@InvincibleEdge

@omarsar0 always the frustrating stuff that gets caught lol

what exactly was the biology question?

4h
Blissy@BlissyOnX

@omarsar0 moving the goalposts for research topics gets exhausting

where does it actually stop?

4h