Minerva introduced for biological discovery using genome language models
Minerva’s creators say it reveals interactions in non-coding DNA, pointing to hundreds of potential new RNAs and repetitive elements per bacterial genome.
TLDR
Minerva’s creators describe it as a discovery method guided by genome language models. They report finding that UG27 reverse transcriptase systems encode variable arrays of diverse non-coding RNAs with a shared structure, each serving as a template for a short DNA hairpin. The team also says Minerva can find and study elements invisible to traditional methods at orders of magnitude greater scale than before.
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