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Bacterial biofilms in arterial plaques may play a role in heart attacks

A post citing a 2025 study says researchers detected traces of oral bacteria in arteries of patients who died suddenly or underwent surgery for advanced atherosclerosis.

MassimoMA
1 Source, 366d ago, first seen 366d ago

TLDR

A post describing research from Finland and the UK says bacterial biofilms may lie dormant inside arterial plaques. It suggests that a viral infection or stress could activate the bacteria, causing inflammation that may rupture a plaque and lead to a heart attack. The post says the findings could eventually inform new diagnostics, treatments or vaccines.

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319.3K

1 Source, first seen 366d ago

4K likes184 comments1.7K saves910 reposts

Combined views

319.3K

1 Source, first seen 366d ago

4K likes184 comments1.7K saves910 reposts

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1 Source

Massimo@Rainmaker1973Infections could be the real cause of heart attacks. Heart disease has long been blamed mostly on cholesterol, clogged arteries, and high blood pressure. But new research from Finland and the UK has revealed something shocking: hidden bacterial colonies may be quietly setting the stage for heart attacks. Deep inside arterial plaques, scientists have found bacterial biofilms – sticky, gelatinous clusters that can lie dormant for decades. Protected from the immune system and antibiotics, they sit in silence until something wakes them up. It could be a viral infection. It could be stress. But once activated, these bacteria trigger inflammation so severe that the plaque can rupture. The result? A sudden blood clot and, often, a heart attack. Researchers detected the genetic fingerprints of oral bacteria inside the arteries of patients who had died suddenly and in those undergoing surgery for advanced atherosclerosis. In some cases, they even caught bacteria breaking free from the biofilm during a heart attack, with the immune system reacting in real time. This discovery adds a new layer to our understanding of heart disease. If infections play a role, new diagnostics, treatments, and even vaccines might one day help prevent the world’s deadliest condition. ["Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques." Journal of the American Heart Association, 2025]366d
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    1 Source

    Massimo@Rainmaker1973Infections could be the real cause of heart attacks. Heart disease has long been blamed mostly on cholesterol, clogged arteries, and high blood pressure. But new research from Finland and the UK has revealed something shocking: hidden bacterial colonies may be quietly setting the stage for heart attacks. Deep inside arterial plaques, scientists have found bacterial biofilms – sticky, gelatinous clusters that can lie dormant for decades. Protected from the immune system and antibiotics, they sit in silence until something wakes them up. It could be a viral infection. It could be stress. But once activated, these bacteria trigger inflammation so severe that the plaque can rupture. The result? A sudden blood clot and, often, a heart attack. Researchers detected the genetic fingerprints of oral bacteria inside the arteries of patients who had died suddenly and in those undergoing surgery for advanced atherosclerosis. In some cases, they even caught bacteria breaking free from the biofilm during a heart attack, with the immune system reacting in real time. This discovery adds a new layer to our understanding of heart disease. If infections play a role, new diagnostics, treatments, and even vaccines might one day help prevent the world’s deadliest condition. ["Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques." Journal of the American Heart Association, 2025]366d
    Today's Rank

    #14

    Today's Rank

    #14