Prime assembly for targeted DNA integration and rearrangement
Nature describes an RNA-guided method for inserting medium-to-large DNA sequences into human cells without requiring breaks in both DNA strands.
TLDR
A Nature research paper describes prime assembly for targeted DNA integration and rearrangement. Nature says the method enables RNA-guided insertion of medium-to-large DNA sequences into human cells without requiring double-strand DNA breaks or progression through the cell cycle.
Prime assembly for targeted DNA integration and rearrangement
Nature describes an RNA-guided method for inserting medium-to-large DNA sequences into human cells without requiring breaks in both DNA strands.
TLDR
A Nature research paper describes prime assembly for targeted DNA integration and rearrangement. Nature says the method enables RNA-guided insertion of medium-to-large DNA sequences into human cells without requiring double-strand DNA breaks or progression through the cell cycle.