Experimental CRISPR infusion reportedly cut LDL cholesterol 52.5% after a year in four highest-dose patients
A post citing CNN says the Cleveland Clinic trial enrolled 15 people with lipid disorders resistant to medication. At the highest dose, triglycerides also fell 47.8%.
TLDR
A post citing CNN says four patients given the highest dose of CTX310 had a 52.5% drop in LDL cholesterol after one year. The experimental CRISPR treatment edits the ANGPTL3 gene in liver cells. Researchers reported no serious adverse events related to the therapy over 12 months and plan 15 years of safety follow-up.
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