A post describes a study published in Nature on September 16, 2026, introducing a platform called “developmental xenocortication.” Researchers engineered mice in which much of the neocortex and hippocampus did not develop normally, creating space for human cortical organoids derived from stem cells. According to the account, the transplanted tissue survived, expanded, developed multiple human cortical cell types and formed functional connections with the mouse nervous system. The post says researchers also used the model to study hypoxia—low oxygen—revealing vulnerabilities in developing human cortical cells that differed from conventional mouse models.