Researchers create 'SpudCells'—synthetic cells that grow, replicate, divide, and undergo selection
University of Minnesota researchers assembled synthetic cells from non-living chemicals: lipid membranes, ~90 kb synthetic genomes, enzymes, and ribosomes. SpudCells grow via feeder vesicle fusion, replicate DNA, divide through membrane buckling, and demonstrate selection as variants outcompete others.
TLDR
This milestone represents significant progress toward building living systems from chemical components, with implications for understanding life's minimal requirements and origins. The open-source design enables further development by the research community. Potential applications span medicine, biofuel production, and biosynthesis, while the work reveals insights into minimal genome function and cellular self-organization—fundamental questions at the intersection of biology, chemistry, and engineering.
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