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A risk variant reportedly creates a new CTCF site
A post says Oxford’s MCCv maps chromatin at base-pair and single-allele resolution, with findings from 405 immune enhancers.
TLDR
A post says Oxford’s MCCv maps chromatin at base-pair and single-allele resolution. It says researchers found a risk variant among 405 immune enhancers that creates a new CTCF site and blocks SESN3, linking the change to autoimmunity via tryptophan and mTOR.
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