Report
Sirtuin-3 may help predict how tumor cells respond to mitocan drugs
Sputnik, citing the Russian Science Foundation, says high sirtuin-3 levels were linked to resistance in lung cancer, ovarian cancer and neuroblastoma cell lines.
TLDR
Sputnik reports, citing the Russian Science Foundation, that Russian and Swedish scientists identified sirtuin-3 as a possible biomarker for response to mitochondria-targeting mitocan drugs. In cancer cell-line tests, reducing the protein made resistant cells sensitive to treatment, while increasing it made sensitive cells more resistant.
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