ScienceCell senescence may be a treatment target for chronic intracellular infection
A Nature Communications study identifies DNA damage caused by Mycobacterium abscessus as a driver of cell senescence through the reprogramming of alveolar macrophages.
TLDR
A study in Nature Communications describes cell senescence as both a hallmark of chronic intracellular infection and a therapeutic target. It identifies DNA damage caused by Mycobacterium abscessus as driving senescence through the reprogramming of alveolar macrophages, immune cells in the lungs.
Cell senescence may be a treatment target for chronic intracellular infection
A Nature Communications study identifies DNA damage caused by Mycobacterium abscessus as a driver of cell senescence through the reprogramming of alveolar macrophages.
TLDR
A study in Nature Communications describes cell senescence as both a hallmark of chronic intracellular infection and a therapeutic target. It identifies DNA damage caused by Mycobacterium abscessus as driving senescence through the reprogramming of alveolar macrophages, immune cells in the lungs.