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    Google DeepMind releases AlphaProtein Novo for small-molecule enzyme design

    Google DeepMind says it developed the pipeline on standard model reactions and validated designs in its wet lab.

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    TLDR

    Google DeepMind announced AlphaProtein Novo, an enzyme-design pipeline developed with the Frances Arnold and Peng Liu research groups. It says it developed the system on a few standard model reactions and validated designs in its wet lab. To challenge it with nascent chemistries, the team asked leading biocatalysis scientists about partnering on reactions they cared about.

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    Combined views

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    4 Sources, first seen 2h ago

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    4 Sources

    @ZvxyWuIn collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProtein Novo, a pipeline for small-molecule enzyme design. We developed AlphaProtein Novo on a few standard model reactions, and validated designs in our own wet lab. We then wanted to challenge this system against nascent chemistries, so we asked leading scientists in biocatalysis whether we could partner on the reactions they cared about.2h
    @francesarnoldThis has been a wonderful collaboration with @GoogleDeepMind to make new-to-nature #enzymes. Great work from the whole team.1h
    @ank_parikhRT @ZvxyWu: In collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProte…1h

    4 Sources

    @ZvxyWuIn collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProtein Novo, a pipeline for small-molecule enzyme design. We developed AlphaProtein Novo on a few standard model reactions, and validated designs in our own wet lab. We then wanted to challenge this system against nascent chemistries, so we asked leading scientists in biocatalysis whether we could partner on the reactions they cared about.2h
    @francesarnoldThis has been a wonderful collaboration with @GoogleDeepMind to make new-to-nature #enzymes. Great work from the whole team.1h
    @ank_parikhRT @ZvxyWu: In collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProte…1h