Inductive Bio launches Beacon-2 to predict human drug doses from chemical structure
The launch announcement describes a shift from Beacon-1’s models for individual molecular properties to a single system for end-to-end human dose prediction.
TLDR
Inductive Bio’s launch announcement says Beacon-2 predicts human drug doses directly from chemical structure using three configurable modules. Across 20 drug programs running through Inductive, it reports a Spearman correlation of 0.61 between Beacon-2’s predictions and dose predictions derived from experimental data. The announcement reports a Spearman correlation of 0.79 in a similar study of 325 publicly available compounds from the ExpansionRx OpenADMET competition.
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Inductive Bio launches Beacon-2 to predict human drug doses from chemical structure
The launch announcement describes a shift from Beacon-1’s models for individual molecular properties to a single system for end-to-end human dose prediction.