Original post
Anshul Kundaje#1650
Diego del Alamo@DdelAlamo
Despite the huge amount of training data, ESM-C is still unable to distinguish mean-pooled CDRH3 representations of real antibodies from those of antibodies w/ scrambled CDRs. Only VHHBERT seems to do this, and only for natural sequences
3:59 AM · Jun 9, 2026 · 5.5K Views