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    FoldDir’s structure-guided approach to protein sequence design

    A post praises FoldDir’s computational results and reports some functional nanobody redesigns.

    KK
    1 Source, 14d ago, first seen 14d ago

    TLDR

    A post describes FoldDir as a flow-matching model that uses protein structure to guide sequence design. It calls the computational results “excellent” and reports some functional nanobody redesigns.

    Combined views

    3.5K

    1 Source, first seen 14d ago

    63 likes

    Combined views

    3.5K

    1 Source, first seen 14d ago

    63 likes
    1 comments
    44 saves
    9 reposts

    Sentiment

    Positive——Negative

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    1 comments
    44 saves
    9 reposts

    Sentiment

    Positive——Negative

    Summary

    Not enough discussion yet.

    No sentiment analysis available yet.

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    1 Source

    @KevinKaichuangFoldDir: A flow-matching structure-conditioned protein sequence design model with excellent computational results and some functional nanobody redesigns. @AlpTartici @MichaelCJewett @Rbaltman

    1 Source

    @KevinKaichuangFoldDir: A flow-matching structure-conditioned protein sequence design model with excellent computational results and some functional nanobody redesigns. @AlpTartici @MichaelCJewett @Rbaltman