/AI20h ago

AI Generative Models Drive Rapid Progress in Drug Discovery

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Andrei Bursuc @CVPR@abursuc#1577inAI

The big hope put simply #cvpr2026

Drugs take incredibly long time to discover, trial, approve: 10 years to patient, $2B per drug, and 9/10 drugs fail in the end #cvpr2026

1:57 PM · Jun 5, 2026 · 780 Views
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Users are excited about generative models aiming to design drugs for all diseases instantly because scaling laws promise highly optimistic progress over the next decade.

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@Latent_Labs Of course, they have an agent Latent-Y that can do all sorts of tasks: antibody design and interaction with Latent-X2, fetching info from literature. It gives up to 50x speedups #cvpr2026

@Latent_Labs Much effort is invested in making producing drug-like generation but also improving screening efficiency with genAI #cvpr2026

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However progress in the past 5 years has accelerated. Simon gives a historical review #cvpr2026

The big hope put simply #cvpr2026

20hViews 59Likes 0Bookmarks 0

The AlphaFold2 architecture in a nutshell: a beautiful mix of AI and domain experience poured there, eg. the evoformer block uses a tweaked attention to take into consideration the structure and interactions in proteins #cvpr2026

19hViews 46Likes 1

Protein mutation analogy to computer vision: as if a single wrong pixel could break an image #cvpr2026

Now a clear and quick intro to proteins (what are they, their structure, how they work). Checking badge … yes, we’re still at #cvpr2026

20hViews 61Likes 0Bookmarks 0

@Latent_Labs Utimately these predictions are tested in wet labs and Latent-X1 did well #cvpr2026

Behold the prediction of Latent-X1, the first foundation model of @Latent_Labs #cvpr2026

19hViews 57Likes 0Bookmarks 0

Now a clear and quick intro to proteins (what are they, their structure, how they work). Checking badge … yes, we’re still at #cvpr2026

However progress in the past 5 years has accelerated. Simon gives a historical review #cvpr2026

20hViews 54Likes 0Bookmarks 0

The decades-long protein folding problem and how crazy the AlphaFold series of models performed #cvpr2026

20hViews 54

Behold the prediction of Latent-X1, the first foundation model of @Latent_Labs #cvpr2026

An analogy between how Imagenet ultimately enabled generative models and how the CASP challenge and then Alphafold let to generative protein design #cvpr2026

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An analogy between how Imagenet ultimately enabled generative models and how the CASP challenge and then Alphafold let to generative protein design #cvpr2026

For the generation, the protein binders are key and to model that they treat atoms as point clouds (it’s still worth studying 3d and point clouds, folks) #cvpr2026

19hViews 48Likes 0Bookmarks 0

@Latent_Labs Much effort is invested in making producing drug-like generation but also improving screening efficiency with genAI #cvpr2026

@Latent_Labs Utimately these predictions are tested in wet labs and Latent-X1 did well #cvpr2026

19hViews 47Likes 0Bookmarks 0

For the generation, the protein binders are key and to model that they treat atoms as point clouds (it’s still worth studying 3d and point clouds, folks) #cvpr2026

19hViews 42

@Latent_Labs A highly optimistic view for the next 10 years. Go go @Latent_Labs! #cvpr2026

@Latent_Labs Of course, they have an agent Latent-Y that can do all sorts of tasks: antibody design and interaction with Latent-X2, fetching info from literature. It gives up to 50x speedups #cvpr2026

19hViews 128Likes 1Bookmarks 0