/AI2h ago

Microsoft's Lorin Crawford details Project Ex Vivo, an AI framework mapping cancer cell dynamics for personalized therapies

The framework analyzes cellular responses to physical microenvironments.

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Original postPeter Lee#1384
Microsoft@Microsoft

New findings in Nature Methods highlight how Project Ex Vivo is helping researchers uncover patterns in cell behavior that may lead to more personalized therapies for patients dealing with cancer.

Microsoft researcher Lorin Crawford explains more: https://msft.it/6006vgDS8

9:30 AM · Jun 9, 2026 · 10.9K Views
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Many users praised Microsoft's AI research on cell patterns for advancing personalized cancer therapies and potential cures, while some criticized leadership and stock performance instead.

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Satya Nadella@satyanadella

Today in @naturemethods, we shared research on how AI can help us better understand cell behavior, offering new insights into why cancer medicines do not work the same for everyone.

By learning more about cell state — how individual cancer cells respond to their surroundings — we have the potential to match therapies more precisely to each patient and improve outcomes. https://news.microsoft.com/signal/articles/why-dont-cancer-medicines-work-the-same-for-everyone-ex-vivo/

1hViews 17.8KLikes 155Bookmarks 19

@satyanadella @naturemethods AI should solve real life problems not some digital only problems

AI started as the protein development software should continue it's impact on medicine and biology

Thanks for supporting life sciences AI

1hViews 47Likes 1Bookmarks 1
Vaibhav Keer@MrVaibhavKeer

@Microsoft Hope we soon find a cure for all kind of fucking cancer

2hViews 26Likes 1
Elena Meier@Elena06vibes

@satyanadella @naturemethods Huge potential here, but the proof will be generalization across diverse cohorts. If the models validate outside the original lab, this could really change treatment matching.

1hViews 70
A. Rahim@Duretum

@satyanadella @naturemethods The key challenge is not predicting cell behavior, but capturing its context dependence at scale.

1hViews 42
Anders B. Eriksen@AndersBEriksen2

@satyanadella @naturemethods Great to see AI accelerating breakthroughs where they matter most.

1hViews 35
Aaron@dicemanorama

@satyanadella @naturemethods

1hViews 26
Venuteju36@venuteju36

@satyanadella @naturemethods I need help sir please help me 🙏😭

1hViews 24
Avais Aziz@avaisaziz

@satyanadella @naturemethods This cell state approach to modeling individual cancer cell responses to their microenvironment is a strong step toward explaining heterogeneous drug efficacy. Looking forward to the Nature Methods details on the AI methods.

1hViews 22
Aswin John Solomon MD@DrAswinSolomon

As an Oncologist observing this, This may ultimately prove to be one of the most important applications of AI in oncology.

For decades, we classified cancers by where they arose:

Breast.

Lung.

Colon.

Pancreas.

Then we learned to classify them by mutations.

Now we are entering a third era:

Classifying cancer by cellular state.

Two patients may carry the same diagnosis.

The same mutation.

The same stage.

Receive the same drug.

Yet have completely different outcomes.

Why?

Because cancer is not a static photograph.

It is a living, evolving ecosystem.

Every tumor contains millions of cells making different decisions in real time.

Understanding those cellular states may help explain why some patients experience extraordinary responses while others derive little benefit.

This is where AI becomes transformative.

Not because it replaces physicians.

Not because it replaces scientists.

But because it can recognize patterns across billions of biological interactions that no human mind could ever process alone.

The future of oncology may not be asking:

“What cancer does this patient have?”

But rather:

“What is this cancer doing right now?”

That shift is profound.

If we can understand cell state, predict resistance before it occurs, and match therapies to the evolving biology of each patient’s tumor, precision oncology becomes truly precise.

The greatest challenge in cancer medicine has never been killing cancer cells.

It has been understanding them.

AI is giving us a new language to read the hidden conversations occurring inside tumors.

And once we can read those conversations, we may finally learn how to change their ending.

The future of cancer care will not be built by biology alone or computation alone.

It will emerge from the convergence of both.

And that future is arriving faster than most people realize.

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Bobby@stocksandbjj

@satyanadella @naturemethods Satya, come on, and support your investors. MSFT is one of the most held stocks by retail investors and frankly this has been embarrassing. 12% down in a straight line.

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Robert’s Opinion@robert65996

@satyanadella @naturemethods You should lose your job. @Microsoft stock performance is pathetic and you are the captain of this floundering ship.

1hViews 4Likes 1
YSA@ysadvisor25

@satyanadella @naturemethods when are you defunding AI to save american jobs?

1hViews 14
Maryna Deundiak, PhD@marynadeundiak

@satyanadella @naturemethods The biggest breakthrough may be understanding why the same treatment creates different outcomes.

1hViews 11
ELOR 🦅@Gestionaireelor

@Microsoft

2hViews 10
Brahim Outaleb-ali@BrahimOuta9hl5

@satyanadella @naturemethods @satyanadella please sir help https://whydonate.com/fundraising/master-degree-

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