2d ago

Alex Peysakhovich urges AI researchers to shift to biology

0

Alex Peysakhovich, partner at Sutter Hill Ventures and former Meta FAIR scientist, posted that AI researchers should consider moving into biology. He highlighted large pretraining datasets that enable experiments without heavy cluster optimization and an active post-training phase where lab validation serves as the main benchmark. Existing AI tools have already accelerated biological work. Engineer Bilal reposted the message, while Michelle Lee quoted it and noted that large-scale post-training capabilities will soon become available.

Original post

if you’re an ai researcher you should really consider working on bio pretraining is great: data sets are big enough for interesting stuff but not so big you’re spending all your time on weird cluster optimization post training is in the age of research: the lab is the only true validation, but it’s expensive so figuring out the limits of what we can do for evals in silico is still very open question existing stuff kind of works: we have proof of life for the ability of ai to accelerate bio but there is a long way to go it feels a lot like computer vision after imagenet or nlp after the first transformers started really working if your idea works, you might get to help improve the human condition. way cooler to talk about at parties than “we pushed benchmark X for chat model Y up by 3 point”

9:38 AM · May 14, 2026 View on X
Reposted by

and soon we will provide post training at scale

alex peysakhovichalex peysakhovich@alex_peys

if you’re an ai researcher you should really consider working on bio pretraining is great: data sets are big enough for interesting stuff but not so big you’re spending all your time on weird cluster optimization post training is in the age of research: the lab is the only true validation, but it’s expensive so figuring out the limits of what we can do for evals in silico is still very open question existing stuff kind of works: we have proof of life for the ability of ai to accelerate bio but there is a long way to go it feels a lot like computer vision after imagenet or nlp after the first transformers started really working if your idea works, you might get to help improve the human condition. way cooler to talk about at parties than “we pushed benchmark X for chat model Y up by 3 point”

4:38 PM · May 14, 2026 · 31.9K Views
10:07 PM · May 14, 2026 · 2.9K Views

if you’re an ai researcher you should really consider working on bio

pretraining is great: data sets are big enough for interesting stuff but not so big you’re spending all your time on weird cluster optimization

post training is in the age of research: the lab is the only true validation, but it’s expensive so figuring out the limits of what we can do for evals in silico is still very open question

existing stuff kind of works: we have proof of life for the ability of ai to accelerate bio but there is a long way to go

it feels a lot like computer vision after imagenet or nlp after the first transformers started really working

if your idea works, you might get to help improve the human condition. way cooler to talk about at parties than “we pushed benchmark X for chat model Y up by 3 point”

4:38 PM · May 14, 2026 · 31.9K Views

@jvarga92 just work with a biologist, the whole point of a team is that not everyone can do every role

6:58 PM · May 14, 2026 · 796 Views
Alex Peysakhovich urges AI researchers to shift to biology · Digg