physorg.com — To help protect its genes, a cell is highly selective about what it allows to move in and out of its nucleus. Yet that choosiness is regulated by just a thin barrier, perforated with tiny transport machines called nuclear pore complexes: protein-coated holes surrounded by flimsy, unfolded protein strands.
Jan 6, 2009 View in Crawl 4
perfect007Jan 7, 2009
really very good news...
roddackJan 7, 2009
“Our machine doesn’t work as well as the nuclear pore complex. We’ve had only three years, while nature’s had billions of years to do this,” Chait saysLies we all know that the Earth is only 6,000 years old/sarcasm
1807Jan 7, 2009
I thought it was going to be an airplane... I guess that wouldn't be news though would it?
paranor01Jan 7, 2009
For everyone really.What the article is basically describing, is a synthetic filtration system based on nature at a molecular level. This has implication of use for pharmaceuticals, waste cleanup, infectious disease control, etc.One possible use would be a new dialysis machine that might be able to filter out certain cells from the blood. Good news for cancer, AIDS, etc sufferers.At least, that's what I understood from the article.
drunkenoafJan 7, 2009
Actually, this is fairly f**king amazing research. It's published in Nature, and FTA this was done by one post-doc. Imagine being able to do that even 5 years ago.Implications are huge; this plus decent gene therapy you could make a transporters to do fairly imporant things-- like pumping out K+ in hyperkalemic patients with renal failure (these tranplanted organs are fairly hard to come by)-- or a transporter tha pumps antibiotics back into bateria (a reverse MDR protein). Clever!
infogainuserSep 8, 2009
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