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218 Comments
- snootywaiter, on 10/16/2009, -2/+138And Marijuana is still illegal? *****.
- twiztidsinz, on 10/16/2009, -12/+113I'll take the OxyContin! It's endorsed by Rush Limbaugh!!
- gankige, on 10/16/2009, -5/+89This *****'s no joke. I know a lot of kids that have gotten hooked on it, and it's only ended in a sad story.
- Rainemaker, on 10/16/2009, -1/+67South Florida (actually referenced in the video) is r a m p a n t with oxy's or "roxy's" as they're usually called. 5-15 dollars a pill is the usual price. They're so bad, the backlash has resulted in a black market on suboxone, the drug used to get off oxy's. Users get prescribed suboxone, and then sell it to people genuinely trying to get off oxy's in order to buy more oxy's for themselves.
It's *****. - cheddaro, on 10/16/2009, -13/+63I was on an Amtrak train once next to a guy shooting up Oxycontin. A total stranger. I said "Hey, whats that you got there?" and he breaks me up a line of Oxycontin to snort.
Boy, that was some pretty awesome stuff. It was like the most relaxed you've ever felt, times 1000.
Done it a few times since, but I really can't be near the stuff. It's the one drug that I could see becoming addicted to very easily. Dangerous *****. - inactive, on 10/16/2009, -6/+50Thanks captain obvious for telling us that 2 different substances are going to have different chemical makeups.
They both do the same thing. - pablocblanco, on 10/16/2009, -20/+61I'll stick to cigarettes and cocaine, thanks though.
- swamp916, on 10/16/2009, -1/+42Oxycontin is a hell of a thing. I got a DUI for Oxy 2 years ago and it is still ***** me over financially, and in other ways such as trouble getting a job, and inability to drive ect. Thankfully I was able to quit and able to cut myself off from the people I used to hang out with but unfortunately my friends haven't been that lucky. No parent should bury their 20 year old due to prescription pills that are so easy to get and extremely hard to quit. When I went to DUI school my drug counselors told me that from their experience OC is one of the hardest drugs to kick and that the withdrawals are as bad if not worse than heroin.
Its not just rich people who can afford expensive pills either, where I come from my friends and their parents were equally addicted to the *****. Sometimes it starts with a legitimate health problem which just leads to abuse and addiction and parents even openly share their pills or have their children sell them for them. How is it that pharmaceutical companies are making millions off of keeping us sick and addicted, yet weed is still illegal? And those companies are the reason why we can't have health care for all? - cheddaro, on 10/16/2009, -2/+38Yeah, just right next to me. And for all he knew I could be a cop or anything else. It was pretty bizarre.
I've seen some other pretty bizarre ***** on the train though too. A cross country Amtrak trip is always an experience... - wabkia, on 10/16/2009, -1/+35He was shooting up in public? Hahaha.
- implied, on 10/16/2009, -9/+35Clearly you haven't (ab)used either one. This information is irrelevant. You get ***** up on both, and they're both extremely addicting.
- Redmo0n, on 10/17/2009, -0/+26You snorted oxycontin given to you by a stranger while riding the train. Diggers are hardcore.
- brianbb98, on 10/17/2009, -0/+24but this is medicinal.
/s - ElAmo, on 10/17/2009, -2/+22and mushrooms still illegal? *****
- danxmason, on 10/16/2009, -15/+35You think THAT's bad... remember the time I had dinner with Gary Coleman?
- anonymouslives, on 10/17/2009, -3/+23Yeah, blame the companies that make the drugs for patients who are actually in real pain, such a cancer, when you and your friends were the ones who CHOSE to abuse the drugs and risk your lives. No one FORCED you to.
- maurovz, on 10/16/2009, -6/+25I enjoyed your comment
- bluddystool, on 10/16/2009, -1/+20People always complain when we're skeptical of fake oxycodone prescriptions in the pharmacy. It's usually sketchy when they're not a usual customer and they're paying out of pocket for it. We sometimes tell them we're out of stock and apologize (usually not far from the truth), but they will keep going to different pharmacies until someone falls for it.
- coachmcguirk, on 10/16/2009, -6/+23Actually... ***** it.. give me both...
- StephanCom, on 10/17/2009, -2/+19"if manatees were washing up on our shores, there would be an outrage"
Well, yeah, manatees are endangered. Junkies aren't. - viet10, on 10/16/2009, -2/+18they all act on opioid receptors, some with higher affinity, but that's not the only thing driving substance dependence. oxycodone is more readily available and easier to take (orally vs iv or im.)
- swamp916, on 10/16/2009, -7/+23Damn I couldn't even watch anymore after I saw the guy smoke it... brings back really horrible memories and it makes my skin crawl to remember the person I used to be when I was addicted to the *****.
Rest in peace Tommy and Justin we still miss you and think about you everyday. ***** the companies that profit off of these types of addictions. - Xenogis, on 10/16/2009, -1/+17yellow skin means liver problems, probably caused by APAP in the pills he was taking
as to him just sitting there chilling, that is nice to do when you are on opiates... - Toenail37, on 10/17/2009, -0/+14Don't forget Rush Limbaugh.
- yocouchdigga, on 10/16/2009, -3/+17Glad you enjoyed it brother!
Got a buck to spare? Been down on my luck lately and I'm tryin to get right with jesus - mulling, on 10/16/2009, -3/+16The problem is, most people in their day-to-day lives are more like the rats trapped in cages than like the ones living in Rat Park. Most heroin addicts would probably spontaneously quit if you suddenly sent them to live in a five-star resort.
- screensnot, on 10/17/2009, -1/+14He was a sad story long before the drugs.
- bluddystool, on 10/16/2009, -0/+12APAP is acetaminophen (the active ingredient in Tylenol) and is not found in OxyContin. Percocet, however, has both oxycodone and acetaminophen PURPOSELY. OxyContin is simply an extended-release tablet of oxycodone.
- bluddystool, on 10/17/2009, -0/+11It's not that black and white. First off, you do not always have the time to verify every sketchy script. Only the pharmacists can do this and often times it is very busy. Fakers know this. There are signs you watch out for. For example, many choose to come in on a weekend when doctor's offices are CLOSED. You therefore cannot verify it immediately. This, of course, is not a determining factor, but is taken into account. If it is a usual customer, we can check their history. However, MOST people with fake scripts have never been to the pharmacy before because they spread out the pharmacies they choose to scam. Plus, they often do not provide insurance, which is another sign. Insurance companies keep track of how much of the narcotics you can get in a certain time frame (as they do with just about every drug they cover). You cannot go around random pharmacies with fake scripts and use insurance because it will obviously be rejected. People with fake scripts will generally always pay cash for it. (And OxyContin ain't cheap!) Often when we tell them we need to verify it (on weekends we will need to wait until the next day the doc's office in question is open) they will casually take the script back and leave. Whether or not the person has faked it, there are always other pharmacies they can/will try. It is the pharmacist's call in these situations whether or not to fill the script because their license is on the line. It is better to deny a super-sketchy script than risk it turning out to be a fake and loosing your license.
http://www.theangriestpharmacist.com/2008/11/05/bu ...
This blog mentions other things pharmacists may do in these situations. It's their call on how they chose to handle it. - AiR1890, on 10/16/2009, -3/+14Yet marijuana is illegal and stupid ***** dea agents try to arrest people who use it because it is the only thing that works without all the ***** attached to it like "legal" prescription drugs, which are safe, because the FDA has said it is safe enough for use.
- ElAmo, on 10/17/2009, -1/+12clearly you have not licked a toad...
- Pseudo99, on 10/16/2009, -5/+16A friend of mine who was a pill popper got a handful of those one time. He was taking them for a few days, when I realized his skin was turning yellow-ish and I would find him on the same place on the couch for 6-8 hours at a time. Not sleeping there, just kind of chilling, not realizing what was going on. I'd recommend staying away from that stuff.
- hikaruzero, on 10/17/2009, -0/+11Care to clarify? It would be nice to have a "and here's why ..." instead of just "I'm a real-life psychiatrist and I say so, therefore it must be true."
- graphak, on 10/17/2009, -2/+11Synthetic WTF, Natural FTW.
- weirddave, on 10/17/2009, -1/+10I think that would be the one time that he wouldn't talk in all caps.
- christoast, on 10/16/2009, -1/+10You don't know what you're talking about, why are you commenting?
- bipolarruledout, on 10/17/2009, -1/+10Look at who law enforcement is targeting. Do you really think it's constructive or cost effective to continue running a prison industrial complex? It's all small time dealers and users. It disgusts me to see these people torn away from their families and for what? They certainly aren't going to be cured of addiction in prison. It's absolute insanity that addiction isn't treated as a social problem which would actually cost far less and might actually work. If the goal is to lock up as many people as possible then congratulations, mission accomplished.
- bluddystool, on 10/16/2009, -0/+8Could have very well been Percocet then.
- wilhoitm, on 10/17/2009, -3/+11"OxyContin or Heroin? I'll take OxyContin!", said Rush Limbaugh!
- leamanc, on 10/16/2009, -0/+8That's why OxyContin is preferred to oxycodone+APAP. It's pure oxycodone, no fillers, nothing else except for a time-release gel...that is easily defeated by chewing or breaking up the pill.
Watch out kids, this drug will take over your life before you know it. I've seen people hit rock bottom because of a OxyContin habit faster than just about any other drug out there (except for maybe methamphetamine). That said, I do believe it is a beneficial drug for what it is intended for--chronic pain--taken the way it is prescribed, without defeating the time-release. - Javali, on 10/17/2009, -0/+8Sure, I can clarify. I usually try not to bore the ***** out of people unless they want me to. There are multiple reasons for the phenomenal addictive properties of heroin over other opioids.
1. Bioavailability (the ratio of medication ingested that is available to the system, usually expressed on percentage) - Since heroin is usually used IV, the bioavailability is nearly 100%. IV meds tend to have a quick onset of action and a higher bioavailability because they bypass first-pass metabolism. You could also inject oxycodone, the opioid on Oxycontin.
2. Metabolism - Heroin is metabolized to other active compounds, like the very addictive morphine and 6-MAM. Oxycodone also metabolizes to active compounds.
3. Ability to cross the blood-brain barrier - This one is important because if it is not on your brain it will obviously not make you high (or be analgesic). When used IV, heroin is highly lipophilic, even more than morphine, and it crosses into your brain very easily. Oxycodone is also liphophilic but its molecular structure makes it less so than heroin.
4. Histamine - When used IV, heroin releases histamine, enhancing the "high"
5. Opioid receptor subtypes - This is also important as not all opioids are created equal. We have multiple subtypes of opioid receptors, one subtype receptor family is responsible for analgesia when stimulated, another one causes euphoria and so on... Well, individual medications may have more or less affinity for these particular subtypes. Therefore you some opioid drugs could provide better analgesia than others, and/or as in this case, euphoria (intense high/rush).
Of course all of this argument will be purely theoretical if it wasn't for in vivo data, or studies in real people. It is well documented that when given a choice to former addicts (and other mammals), there is a very strong preference for heroin vs other opioids such as fentanyl, oxycodone, meperidine (Demerol) or other similar drugs. Don't get me wrong, the synthetic opioids, like Oxycontin, are highly addictive but heroin is some serious, serious *****. I have been told by addicts that if you ever try heroin, you'll like it so much that they guarantee you will get hooked.
If anyone is interested in learning more send me a "shout" here on Digg and we can talk more. - marrod1977, on 10/17/2009, -0/+8Really? Then why do rock stars and famous people do more drugs than the average Joe? ...And trash hotel rooms while they're at it?
- swamp916, on 10/16/2009, -1/+8they call it hill billy heroin for a reason...
- evilsin, on 10/17/2009, -0/+7getting your balls licked while on oxycontin is the best high out there, be careful.
- bipolarruledout, on 10/17/2009, -3/+10So what your saying is that you profile your own customers? That sounds much more reasonable than attempting to verify the legitimacy of the script.
- holychicken, on 10/16/2009, -0/+7Look up the difference between the words "is" and "was."
- OverDriven, on 10/17/2009, -0/+6Chemically, yes they are different. As far as addictiveness, action on the brain, and blood brain barrier affinity, you have no idea what you're talking about.
- pablocblanco, on 10/17/2009, -0/+6whose ass do you think I'm doing the cocaine off of?
- PBRbeer, on 10/17/2009, -2/+8and marijuana is still illegal.....
- marcushe, on 10/17/2009, -3/+9It upsets me to see these people being treated as criminals, as we are used to in our "drug war" mindset. These people don't belong behind bars. They belong in hospitals. Why do we put sick people in prison?
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