239 Comments
- JamesMorris, on 04/13/2008, -8/+336If this is true then this is amazing. Much more news worthy than half the stuff on the front page lately.
- smurf22, on 04/13/2008, -6/+318Cancer, Aids, and Alzheimer's has been cured on digg so far.
- keviniskool, on 04/13/2008, -11/+195Yeah, but it mutates everyone into zombies. That's where they get you.
- diggdiggerid, on 04/13/2008, -2/+109This would be more promising if it was published in a peer-reviewed journal instead of a tabloid.
- formergthing, on 04/13/2008, -1/+103Don't forget diabetes - which gets cured about once a week.
- dxgg, on 04/13/2008, -2/+64Anybody read Flowers for Algernon?
- lukas88, on 04/13/2008, -1/+54It is prudent to be skeptical of researchers who go to news outlets before their study is peer-reviewed. At this point, all results are anecdotal and based on case studies. In the article, other alzheimer's research specialists raise red flags about the findings.
Giving people hope is great, but when you are dealing with something that would mean so much to everyone, it is best to be sure before you get everyone excited. - jameshighmore, on 04/13/2008, -1/+39Don't make fun of diabeetus.
- CthulhuDawn, on 04/13/2008, -0/+29I don't trust a damned thing from The Daily Mail. It's pretty much a tabloid.
- oatdc, on 04/13/2008, -1/+30my great uncle has alzheimer's, and if this could become relatively mainstream within a couple years that would be a welcome relief to my family. here's to hope that it works!
- saxreturns, on 04/13/2008, -0/+27http://www.medpagetoday.com/Neurology/AlzheimersDi ...
- ShootTheCore, on 04/13/2008, -1/+27You don't catch Alzheimer's...
- Persian5Life, on 04/13/2008, -1/+26so if you did not bother reading the article and made a comment that means you are uneducated in general; lacking knowledge or sophistication; AKA ignorant.
- carpespasm, on 04/13/2008, -1/+24It's possible. There are many kinds of brain problems that are often very similar in effect to Alzheimer's that can be cured to a great extent pretty quickly (normal pressure hydrocephali comes to mind). Here's to hoping that this is at least a strong help for those who deal with this terrible disease.
- serif69, on 04/13/2008, -2/+24Thanks to Wilford Brimley
- Persian5Life, on 04/13/2008, -2/+22i really want to hug the guy/girl who found this out, a lot of lives are going to be impacted my this drug.
- tj111, on 04/13/2008, -1/+20Either way its ok, Will Smith can save us,
- Arcesius, on 04/13/2008, -0/+18But still we haven't managed to cure the common cold.
- TheFinaleofSeem, on 04/13/2008, -2/+19Don't get your hopes up, guys. This is the Daily Mail we're talking about. I'll believe it when I see some coverage from a real news source, not those sensationalist hacks.
- zspade, on 04/13/2008, -4/+21Way to spread mindless science phobia Kevinskool! Everyone knows it's the cure for cancer that causes zombie apocalypses.
- codaofchoice, on 04/13/2008, -2/+19Then welcome to being dugg down and being a retard. Enjoy.
- jmpeagle, on 04/13/2008, -0/+16and it never will be. You can onlt treat the symptoms. The common cold is endlessly mutating and by the time you are done analyzing it, the prevalent strains have totally changed their genetic makeup and are completely different organisms.
- jmpeagle, on 04/13/2008, -0/+16http://www.jneuroinflammation.com/content/5/1/2/ab ...
Journal of Neuroinflammation 2008, 5:2doi:10.1186/1742-2094-5-2
Published: 9 January 2008
Abstract
Substantial basic science and clinical evidence suggests that excess tumor necrosis factor-alpha (TNF-alpha) is centrally involved in the pathogenesis of Alzheimer's disease. In addition to its pro-inflammatory functions, TNF-alpha has recently been recognized to be a gliotransmitter that regulates synaptic function in neural networks. TNF-alpha has also recently been shown to mediate the disruption in synaptic memory mechanisms, which is caused by beta-amyloid and beta-amyloid oligomers. The efficacy of etanercept, a biologic antagonist of TNF-alpha, delivered by perispinal administration, for treatment of Alzheimer's disease over a period of six months has been previously reported in a pilot study. This report details rapid cognitive improvement, beginning within minutes, using this same anti-TNF treatment modality, in a patient with late-onset Alzheimer's disease. Rapid cognitive improvement following perispinal etanercept may be related to amelioration of the effects of excess TNF-alpha on synaptic mechanisms in Alzheimer's disease and provides a promising area for additional investigation and therapeutic intervention. - Dustin00, on 04/13/2008, -0/+13Just a crazy thought: at 82, if it works with some random, minor side effects, do you care about any negative side?
- whatever01, on 04/13/2008, -0/+12Have you seen a section from an Alzheimer patient's brain? It seems pretty apparent that in advanced stages much of the brain matter is missing. I'm skeptical for this, and for Lukas88's point that this wasn't from a peer reviewed journal.
- Persian5Life, on 04/13/2008, -0/+11i meant to say by*, i was overtaken by joy. someone important to me has Alzheimer.
- credence, on 04/13/2008, -0/+11Knowing my family *is* physical pain. Thank you, you've been a terrible audience.
- jopache1, on 04/13/2008, -0/+11Wrong:
http://digg.com/general_sciences/Hot_Sex_Cures_the ... - formergthing, on 04/13/2008, -3/+14Unfortunately even if it works - if we're just doing clinical trials now we're probably 10 years out on having a publically available cure.
On the bright side, nuclear holocaust will probably happen before then, so it won't matter anyway. - libertinette, on 04/13/2008, -0/+11If I had to choose between that level of pain and not knowing my own family, I would choose the physical pain every time.
- oatdc, on 04/13/2008, -1/+11as bad as that is, i laughed.
- bwebb, on 04/13/2008, -0/+10This news is actually a little old but I'm glad it's getting front page recognition. I don't trust anything from Daily Mail but I found a more informative article from a more reputable source:
http://www.sciencedaily.com/releases/2008/01/08010 ... - dxgg, on 04/13/2008, -0/+10I hope you didn't digg me up...I don't accept kudos from idiots.
- DaFunk, on 04/13/2008, -0/+9It was peer-reviewed.
http://www.pubmedcentral.nih.gov/articlerender.fcg ... - necroprancer, on 04/13/2008, -0/+9I would also add that how convinced these clinicians seemed of their drug's effectiveness was a bit disturbing. A good researcher would never say a drug they're researching is effective until clinical studies bore that out. This all seems a bit underwhelming.
- superyounan1, on 04/13/2008, -1/+10oh please let this go on to be or spawn an official treatment for Alzheimer's, there is nothing more scary to me than the loss of one's dignity and control like this
- junkwheel, on 04/13/2008, -2/+10Hillary says she has a cure which only costs $10.
- Slagtits, on 04/13/2008, -1/+9And the prize for the biggest ***** of the day goes to....................................irvin666.....................well done.
- Torx, on 04/13/2008, -0/+7Another month, another Alzheimer's cure... When are we ever going to see these cures in actuality?? I want my grandmother to remember me before she passes and it would be nice to have this soon.
- jmpeagle, on 04/13/2008, -2/+9just some background info...not passing judgement on conflict of interests or anything
I did a little digging and the head researcher Edward Tobinick, M.D. mentioned in this article owns stock in Amgen, the manufacturer of Etanercept (trade name Enbrel), and has multiple issued and pending patents assigned to TACT IP LLC that describe the parenteral and perispinal use of etanercept for the treatment of Alzheimer’s disease and other neurological disorders, including, but not limited to, U.S. patents 6015557, 6177077, 6419934, 6419944, 6537549, 6982089, 7214658 and Australian patent 758523. - TheIguana, on 04/13/2008, -3/+10As soon as I saw all of the gossip on the right side of the page, this article lost all credability. How can I take this article seriously when there is headline about Britney Spears being depressed right next to it.
- carpespasm, on 04/13/2008, -0/+7I wouldn't say cured, but most people with type 2 diabetes can keep it managed pretty well and often times if they have a weight problem and they lose some weight they can get it to show no symptoms from what I understand.
- BelatedHero, on 04/13/2008, -1/+8Funny. I just watched that episode of the x-files where the orderly was treating the old people in a convalescent home with mushrooms. This sounds more promising.
- Arcesius, on 04/13/2008, -2/+9Are you supposed to be a troll or something?
- fatTJ, on 04/13/2008, -1/+8That was a great book, until they mutilated it with the movie
- MasterPlayer, on 04/13/2008, -0/+7Seriously though, the ***** is with all these "cures"? Why do they never seem to garner the heavy media coverage they should, and why aren't they being employed on everyone with these horrible diseases?
- Intamin, on 04/13/2008, -1/+7Unless you developed it and saw it's magic work firsthand...I don't think it's in the "of course" dept....
I hope it's true though. - greenlight2001, on 04/13/2008, -0/+6This is not a 'cure'... it will not undo the physical changes that take place in the brain of an Alzheimer's patient. It will not remove the amyloid plaques, it will not replace lost brain mass, it will not reconnect the lost neuronal connection. If it helps even a little, then great, I'm all for it, but this is FAR from a cure. I believe in the next 20 years we will see a 'preventative' solution, something that will greatly slow the disease progress or even hold it off completely but I do not believe we will ever (next 100 years) see a process to reverse the full effects of Alzheimer's once it has already happened. Alzheimer's is a lot more complex then a normal pressure hydrocephali. Are you scared of getting Alzheimer's? Eat well, exercise and keep you mind engaged and challenged all through your life. There's some evidence that it will slow down the effects if you are programmed to get it.
- Robbothehood, on 04/13/2008, -0/+6None of the "cures" have panned out it would seem.
- azra3l, on 04/13/2008, -2/+8***** off, hippy
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