79 Comments
- Ninh, on 11/13/2009, -1/+46You too can now become part of the next pandemic by helping flu virii become resistant to treatment! Get your *****-the-world-my-kid-just-sneezed kit now and save 9.95 on our offer!
- mikek814, on 11/13/2009, -3/+32Folks, be smart and leave this task to your pharmacist!!!
From CDC: "A pharmacist can make a Tamiflu® suspension (liquid) using available Tamiflu® adult capsules, which are in not in short supply. CDC is alerting pharmacists about this option and providing instructions on how to prepare a suspension using adult capsules. Some pharmacies, including some chains, can do this already, others are not yet prepared. Children’s doses of Tamiflu® are also available in capsules." - inactive, on 11/13/2009, -0/+17Sounds like a good idea at first, but with H1N1 showing up with resistance to Tamiflu, this might be a bad thing.
- shadowspawn, on 11/14/2009, -1/+17My daughter got the flu, bad. 11 years old, and it cost too much to actually find out if it was swine flu. Since the treatment was the same anyway, I figured seriously, why bother? Why pay the CDC $150.00 to figure out something that didn't make any difference since the medicine was the same?
Whatever she had, she had, and got rid of it after 5 days. The rest of the family didn't get it. I see no real need for Tamiflu.
Just eat well and keep your immune system up. - mysql101, on 11/14/2009, -0/+14I was expecting how to make tamiflu, instead the article is about how to water down tamiflu for a dose for kids.
- cawfee, on 11/14/2009, -0/+12Shot of vodka and three shots of orange juice.
Wait, that's a Screwdriver. Nevermind. - FrozenKetchup, on 11/14/2009, -1/+13As a pharmacist who has had plenty of compounding experience, I can tell you it's not very difficult to do. Most people would do fine, but I guarantee there would be a small percent that either dilute it way too much or not dilute it enough and out of those cases there would likely be a couple that had some serious consequences. Note that the drug is weight based for children and 1 capsule contains 75 mg so unless the kid weighs more than 40 kg you have to pay attention to what your doing. Also if your kid weighs more than 40 kg they should learn how to take a capsule.
- ghatid, on 11/14/2009, -0/+11I thought a screwdriver was 3 shots of vodka and 1 shot of orange juice.
- Jimmysh, on 11/13/2009, -0/+10Now if they just make a way to mix your own vaccine...
- jester55, on 11/14/2009, -0/+9I thought they were going to tell us how to actually make it. I was disappointed, for that would be a useful thing to know. Then again, its probably more complicated than various household ingredients.
- mntbikeracer1, on 11/14/2009, -1/+9I'm working in a pharmacy right now. If your kid is taking the full 75mg then sure go right ahead and open the cap and mix it with something sweet. If you need to dillute the caplets down to make smaller single doses then don't mess with it let the pharmacist do it for you. We go to school for a reason. You need to know what your doing so that you can properly adjust the amount of solution in order to create the mg/ml solution that is needed for your child.
- anthropodeus, on 11/14/2009, -0/+7you know, the article really wasn't that long.
- JiGMeister, on 11/14/2009, -0/+6This could only get nasty
- Taiyoryu, on 11/14/2009, -0/+6Why doesn't adult medicine taste like children medicine? Grape-flavored children's Dimetapp rules. What's with this cherry crap when you graduate to the adult stuff?
- anonymousmedic, on 11/14/2009, -0/+6Vitamin D megadoses are very dangerous, and clinically show no efficacy in preventing H1N1 infection. Vitamin D toxicity is a real issue, since it's a fat soluable vitamin, and actual, true Vitamin D Deficiency (such as Osteomalacia/Ricketts) is incredibly rare in the modern world.
- janinekahn, on 11/13/2009, -0/+6Exactly.
- wbrns, on 11/14/2009, -0/+6Who on earth could ingest the duct tape though?
- xtc46, on 11/14/2009, -0/+5@cherwilco
Thats called a cosmonaut - Jeff901, on 11/14/2009, -1/+6When I was growing up, "children's" medication was unheard of. The doctor prescribed the medication and the dosage was 1/2 a pill. So, now the trick was getting a 4-9 year old to swallow this crap.........
Out came the chocolate syrup into a tablespoon...then into the syrup went a crushed up pill......
After that, we walked to school with no shoes, in the snow, up hill, both ways. (The first part is true...had to add this part) - cherwilco, on 11/14/2009, -0/+4no its 3 shots vodka and a sprinkle of tang
- orangefly, on 11/14/2009, -0/+4www.macgyvermeds.com
- innocentsinner, on 11/14/2009, -0/+4Or *shudder* black licorice.
- Ne007, on 11/14/2009, -0/+3Common adverse drug reactions (ADRs) associated with oseltamivir therapy (occurring in over 1% of clinical trial participants) include: nausea, vomiting, diarrhea, abdominal pain, and headache. Rare ADRs include: hepatitis and elevated liver enzymes, rash, allergic reactions including anaphylaxis, and Stevens-Johnson syndrome.[6][7]
- IglooFu, on 11/14/2009, -0/+3I think I'm fairly smart...
I understood about four words on that page. - atchon, on 11/14/2009, -0/+3If anyone does want to do it themselves and doesn't feel like figuring it out.
(75 mg) ( original volume) = ( desired dosage) (new volume for dilution)
Solve for new volume for dilution. Using http://www.tamiflu.com/taking/default.aspx for dosage for childs weight.
example:
Child is 52-88lbs dosage required is 60 mg. (75 mg) x (1 Teaspoon) = ( 60 mg) x (dilution volume) = 1 1/4 Teaspoon
So break the 75 mg tablet in 1 1/4 Teaspoon of sweet liquid then give child 1 Teaspoon of this mixture for an effective dosage of 60 mg.
Correct me if I am wrong mntbikeracer1. I am sure most people reading this probably are familiar with basic chemistry and could figure it out, but just in case someone did actually want this information. Though you might as well go to the pharmacist and have them do it. - anonymousmedic, on 11/14/2009, -0/+3http://www.nursingtimes.net/nursing-practice-clini ...
http://www.bio-medicine.org/medicine-news/Crushing ...
Basically, that capsule is there for a reason. Some of those reasons are to allow the medicine to release at a controlled rate as it passes through the intestines, to protect an area of the intestine or stomach from harsh effects of a medication, or to allow the medication to survive stomach acid, or to dissolve and release the medication at a certain point in the GI tract. Although there are some medicines that can be readily crushed and administered (and this is a common practice in pediatric, elderly, and tube feeding patients), many out there cannot, and can either cause an overdose, or other adverse effects. For example, Asprin and Ibuprofin is enterically coated for a reason - it errodes the stomach lining. Controlled release oral morphine, when crushed, can cause an overdose. - atchon, on 11/14/2009, -0/+3http://en.wikipedia.org/wiki/Oseltamivir_total_syn ...
Hope you are an organic chemist... - anonymousmedic, on 11/14/2009, -0/+3You can't always crush pills up and give them with liquid, expecially if they are sustained release or enteric coated pills. Otherwise, bad things happen
- twiztidsinz, on 11/14/2009, -4/+7I'm sorry... but if you can't follow the instructions provided by the CDC, I cannot fathom how you can care for a child on a day-to-day basis.
How do I mix the ingredients?
* Pour a small amount (about a spoonful) of a sweet thick liquid into a cup or bowl.
* Holding one capsule over a small bowl, carefully pull the capsule open and pour the complete contents of the capsule into the bowl.
* Stir the mixture and give the entire dose to the child with a spoon. - secrity, on 11/14/2009, -1/+4Didn't you read the article?
- anonymousmedic, on 11/14/2009, -1/+4Children are not little adults. Anyone who tells you they are is an idiot. Children metabolise drugs differently, and require different doses to get the same effects.
People treating kids like little adults is why we have so many Acetamenophen overdoses each year. - pipebender, on 11/14/2009, -0/+3"My daughter got the flu...........Why pay the CDC $150.00 to figure out something that didn't make any difference since the medicine was the same?"
Because that's how antiviral drug resistance built up. - skinny01, on 11/14/2009, -0/+3Just keep it in your mouth and in your nostrils, the germs stick to it instead of going into your system.
- mntbikeracer1, on 11/14/2009, -0/+2There is a lot of misinformation here so I'll supplement my previous comment. Tamiflu is not a vaccine and it does not cure H1N1. It is an antiviral which has been proven effective in helping to reduce duration of H1N1 infection. It is not a miracle cure and most of the time you might as well buck up and just sit it out because the one day difference it may give you often isn't worth the money.
- xero69, on 11/14/2009, -0/+2It's nice to see there are sane parents out there. Save the Tamiflu for life threatening situations, hospitalization, etc.
- darkcrystal, on 11/14/2009, -0/+2http://en.wikipedia.org/wiki/Oseltamivir_total_syn ...
Have fun! - Ne007, on 11/14/2009, -0/+2what is "over 1%" anyways?
- elliotys, on 11/14/2009, -0/+2You can do the same thing with Antabuse tablets :D
- atchon, on 11/14/2009, -0/+2I have a feeling you may one day win a Darwin Award regardless....
- LetterQ, on 11/14/2009, -0/+2The article wasn't about a DIY vaccine, it was about creating a liquid version of Tamiflu for kids, from the capsules, because many pharmacies are out of the children's liquid version. Tamiflu isn't a vaccine, it's a medication that reduces the severity of influenza once you already have it.
For someone making reference to a Darwin Award, you're not too bright yourself. - LetterQ, on 11/14/2009, -0/+2This is something most pharmacists will do for you, but when we brought my 6-year-old son to the pediatrician a couple of weeks ago with Swine Flu, the doctor told us it was perfectly okay to do this ourselves if we couldn't find the children's liquid Tamiflu, and gave us a sheet with the instructions. It's really very simple.
- rossisdead, on 11/14/2009, -0/+2So go out and buy it? It's legal in the US again.
- rcguy69, on 11/14/2009, -0/+2I just survived a harrowing 5 days with a 6 year old with H1N1. We mixed the suspension with chocolate pudding followed by more chocolate pudding mixed with gravol. Within 36 hours his terrible fever broke. For those that think Vitamin D and vitamins will ward it off - it did not for my 6 year old. We'd been following that regime religiously for over a month. The Canadian government picked up the tab for the Tamiflu via the pharmacy so it cost us nothing. Pharmacists are highly trained individuals. Why on Earth would you not ask them to do the job they are trained for?
- anonymousmedic, on 11/14/2009, -1/+3Um. This information is really flawed. You're not actually producing tamiflu, you're compounding and reconstituting powdered tamiflu.
To actually produce Tamiflu would require about sixty kilograms of genetically pure chinese star anine, a propriatry process involving unreleased chemicals and genetically modified E. Coli bacteria that takes about six months to complete, and a microbiologist to do. - nepidae, on 11/14/2009, -0/+2Many times the issue is knowing the right question to ask. If you need liquid tamiflu and when you ask they say they have none, why (previous to now) would you ever guess to ask if they can create it? I expect pharmacists to have a good knowledge of what drugs do, but I never expected to ask if they could liquefy a specific drug /shrug.
- bubba9999, on 11/14/2009, -1/+3put it in a piece of cheese, hold their head up at a tilt, and rub their throat until they swallow it. tell them that they're a good boy or girl while you do that, then let them go outside afterwards.
- guyincognitoo, on 11/14/2009, -0/+2Campbell's chicken noodle soup, DayQuil, and Sprite.
- nepidae, on 11/14/2009, -1/+3You carry around a bag of dicks with you to snack on almost every where you go, show me proof that you don't.
- anonymousmedic, on 11/14/2009, -1/+3You raped and murdered a girl in 1990. Anyone who says otherwise has to show me proof!
- bitbytebit, on 11/14/2009, -0/+1its not mild
you had a cold
by percentage more people have already died from h1n1 than the normal flu -
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