Abnormal thickening and darkening of the skin, especially in

rarediseasesandmedicines.blogs… — Acanthosis nigricans is a disorder that may begin at any age. Acanthosis nigricans is most often associated with obesity or polycystic overian disease in women and it is a condition characterized by abnormal thickening and darkening of the skin, especially in body creases, on the neck, under the arms or in the groin and under the breasts. Acanthosi