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64 Comments
- AmyVernon, on 11/18/2008, -2/+12This is amazing. Truly. My grandfather died of Type 1 (well, truthfully, died of refusing to stick to the proper diet for someone with Type 1), and I know others with Type 1. If there were a way to cure it, that would be fantabulous.
- soupdawg30, on 11/19/2008, -0/+10type 1 diabetes has nothing to do with being overweight
- untitlednet, on 11/19/2008, -4/+13Whew... I was getting worried the month would end without Digg curing cancer again.
- soupdawg30, on 11/19/2008, -0/+9This would be great I have had type 1 diabetes for 11 years now i am only 24 but my body is aging more rpidly because of the high sugar levels I sometimes hve hopefully this will be a cure. Type 1 diabetes is a miserable sickness to have.
- nullcodes, on 11/19/2008, -0/+6Hey see if you can enroll in this clinical trial:
http://www.bayhilltherapeutics.com/T1D.html
Not sure if you have to be in early stage though .. just thought I'd let you know.
Personally I think the cure will come with a combination of stem cell therapy and selectively shutting down the immune cells that specifically target the insulin cells (so u don't relapse). - 9bpm9, on 11/19/2008, -0/+5You know, if we released all of the mice that we've cured diseases in, they would ***** dominate this world.
- BeShirtHappy, on 11/18/2008, -0/+5This sounds just like my grandmother. And yes it would be truly awesome if there was a cure.
- benedictm, on 11/19/2008, -0/+5Hmmmm. I have had diabetes for 24 years (the full on Type 1, not the half assed Type 2) so this is mildly exciting. However will it work on long term sufferers? I thought the disease destroyed the insulin creating cells so although this can halt the disease can it really re-grow dead things? Is so its a miracle.
- indyweb, on 11/19/2008, -0/+4Insulin isn't exactly dirt cheap. I have to pay about $350 per month (counting needles / testing supplies). . not exactly an optional payment either. . insulin kinda sells itself. 350 / month is like a brand new Honda Fit. Somebody is getting paid huge on my inability to process sugar. GD my crappy genetics.
- GlassAgate, on 11/19/2008, -0/+4Did BeaverBoy get your message before eating the stick
of butter? - SpeedSteamBoat, on 11/19/2008, -0/+4Um, this isn't a cure for cancer. It's a cancer drug that cures diabetes.
- nullcodes, on 11/19/2008, -0/+4Any company that comes up with the cure for diabetes will make the shareholders of that company instant multi billionaires .. at which point they can sell their stock.
Imagine they can sell the cure (with financing and govt. aid/grants) at $10,000 a piece (annual AIDS treatment costs more) to the 170 million people with diabetes worldwide. that's a whopping unheard of $1.7 TRILLION dollars. Even if they can sell it to half the victims that still $850 BILLION dollars.
Compare to Microsoft's total cash reserves of all the added profits they've ever made is only 40 billion.
Then they can use their money to form another company to cure some other disease like one of the many cancers.
Without the diabetes cure, the company share price stays stagnant and shareholders don't get as rich cause they are having to sell insulin which is dirt cheap and has razor thin profit margin. - LimeParrot, on 11/19/2008, -1/+4Fantabulous... yes...
- inactive, on 11/19/2008, -0/+3whoops, somebody's getting fired for that one - there's no profit in cures, the real money is in treatment.
- Thinkerofthings, on 11/18/2008, -1/+4Hoefully these particular cancer drugs don't make you sick
- Poobah6, on 11/19/2008, -0/+3I take Sutent for Kidney Cancer. The side effects are along the lines of Chemo. My side effects are managable. I take two pills to keep my blood pressure close to normal. I take Prilosec for GI, issues. I have "magic mouthwash" for mouth sores, and an ointment for tiny sores in my nose.
Many others have problems with fatigue, blisters on hands and feet, changes in blood count, nose bleeds, mouth sores...
My favorite side effect is white facial hair. - DickyT83, on 11/19/2008, -0/+32 cures 1 diabetes.
- HamstaMan, on 11/19/2008, -0/+3And even the connection between weight and type 2 diabetes is a tad bit gray.
It's the crap you eat, not the weight itself that matters the most. Granted that eating crappy food will make you overweight as well as give you diabetes. - nullcodes, on 11/19/2008, -0/+3Any company that comes up with the cure for diabetes will make the shareholders of that company instant multi billionaires .. at which point they can sell their stock.
Imagine they can sell the cure at $10,000 a piece to the 170 million people with diabetes worldwide. that's a whopping unheard of 1.7 TRILLION dollars.
Then they can use their money to form another company to cure some other disease like one of the many cancers.
Without the diabetes cure, the company share price stays stagnant and shareholders don't get as rich cause they are having to sell insulin which is dirt cheap and has razor thin profit margin. - soupdawg30, on 11/19/2008, -0/+3cancer? Not this time
- MiddleOfNowhere, on 11/19/2008, -0/+2Read whatever's available about new treatments. Get in contact with others. Stay critical, but keep a sense of optimism. Try to spread the word when there is a promising treatment on the horizon.
You are not victims. This is the 21st century. - untitlednet, on 11/19/2008, -0/+2Chris Rock said it best:
http://www.youtube.com/watch?v=QWpdl3ITXmYt=38s - nullcodes, on 11/19/2008, -0/+2Any company that comes up with the cure for diabetes will make the shareholders of that company instant multi billionaires .. at which point they can sell their stock.
Imagine they can sell the cure (with financing and govt. aid/grants) at $10,000 a piece (annual AIDS treatment costs more) to the 170 million people with diabetes worldwide. that's a whopping unheard of $1.7 TRILLION dollars. Even if they can sell it to half the victims that still $850 BILLION dollars.
Compare to Microsoft's total cash reserves of all the added profits they've ever made is only 40 billion.
Then they can use their money to form another company to cure some other disease like one of the many cancers.
Without the diabetes cure, the company share price stays stagnant and shareholders don't get as rich cause they are having to sell insulin which is dirt cheap and has razor thin profit margin. - TheMachine1, on 11/19/2008, -0/+2Most health problems are not understood enough to even begin to develop a cure. Its nice the conspiracy nuts have such faith in the pharmaceutical industry that they are smart enough to cure disease but are too greedy to. But the reality is the industry is not smart enough.
- pak314, on 11/19/2008, -0/+2My pet mice thank the researchers for yet another disease cured.
- BotaXero, on 11/19/2008, -1/+3Like "I am Legend"?
- tryangles, on 11/19/2008, -0/+2The question is how do you profit from this without curing someone completely... Remember - it's never about the cure, its only about the comeback.
- Rivetgeek, on 11/19/2008, -0/+2uh what exactly did they make money on with polio? the iron lung manufacturers? There was no treatment dude.
- GlassAgate, on 11/19/2008, -0/+2Begone, conspiracy theorist!
- nullcodes, on 11/19/2008, -0/+2Hey see if you can enroll in this clinical trial:
http://www.bayhilltherapeutics.com/T1D.html
Not sure if you have to be in early stage though .. just thought I'd let you know. - xaogypsie, on 11/19/2008, -0/+2I take Gleevec for chronic myelogenous leukemia, and it does make me pretty sick at times. Usually I am just a little bit tired, with some very small skin discoloration. Other times, it messes my GI tract up in interesting ways. All better than type 1 diabetes, i would imagine, and certainly better than dying from leukemia.
- davidpro83, on 11/19/2008, -0/+2I am going to start taking Gleevac now. What harm could it do? It not like I need anything phosphorylated any time soon
- BoneheadFarker, on 11/19/2008, -0/+2That really sucks. On the other hand, I have a friend who's diabetic. She would gladly take 8-10 weeks of that over having to deal with diabetes like she has the last 20 years.
- mattycoze, on 11/19/2008, -0/+2Type 2 Diabetes can promote similar symptoms to that of type II. In fact after many years of treatment with the common drug classes from sulphonureas, to glibenclamides, they'll start to be put on new insulins anyway.
Stem Cell therapies are another great option for future research, however more needs to be done to find novel pharmacological intervention to mitigate the increased risk factors associated with Diabetes and other metabolic syndromes. However; it's best that that diabetic patients should be proactive about their health, look after their diet and exercise more.
I for one study the effects of chronic hyperglycemia on the heart (the coronary vasodilatory response to myocardial ischemia to be exact). On a molecular cell biological level; is interesting to see what changes are being made to the mechanisms that mediate these effects. - dantana, on 11/19/2008, -0/+2if you've been diagnosed with type 1 diabetes only recently, there are a number of clinical trials that might interest you at http://www.newonsetdiabetes.org
- jjuice, on 11/19/2008, -0/+2Yep, there are theories that if you halt the destruction caused by the immune system, the cells may in fact grow back on their own. Think of it like a leaky bucket that is constantly being filled. If you plug the hole, the bucket should refill. However, if this isn't the case, there are other drugs (in trials today) that may be able to cause the insulin-producing cells to regenerate. They would certainly be more effective if these cancer drugs are able to halt the immune response ( i.e. fill the bucket when the hole is sealed vs. trying to fill the bucket faster than it is leaking).
Anyway, I've been following this type of research for a long time- there are a 100 ways to cure diabetes in mice (at least early-stage diabetes) and none have yet to translate to humans. Still, given all of the current mouse trials that have been able to re-educate the immune system, hopefully one of them will work. - bitbytebit, on 11/19/2008, -0/+2look at the carbs. If you don't have type 1 dont make uninformed comments
- panamajuice, on 11/19/2008, -0/+2I am 33 years old and have been a type 1 diabetic for 18 years. Finally a possible cure!.
- Garofoli, on 11/19/2008, -0/+2This doesn't cure it, but it does put it into submission rendering it the harmless.
- nullcodes, on 11/20/2008, -0/+1Yes but there is no patent on it ..insulin was discovered many many years ago.. one company doesn't have a monopoly on insulin, and so they can't make as money they can't put a high premium on it .. and even if they did .. one company won't get to sell to so many people.
A company that finds the cure will not have to worry about competition because they'll own the patent. - jster89, on 11/19/2008, -0/+1This would be unlikely to help in the case of well established type I diabetes as all of the insulin producing beta-cells in the pancreas have already been destroyed. Stopping the immune reaction at this stage would be unlikely to yield results.
- HamstaMan, on 11/19/2008, -0/+1Hmm. I think the goverment is putting subliminal messages in my milk that makes me wanna punch people that uses the term "tin foil" in the face.
- GlassAgate, on 11/21/2008, -0/+1Begone, conspiracy theorist!
"Richard Nixon declared a "War on Cancer" in something like 1977, why isn't it cured yet?"
Perhaps we didn't have the technology necessary to study it properly for a couple of
decades, and after we discovered it, found a few more hurdles to go over. Not everything
has a simple answer. Think back to answering questions for a homework assignment.
Some had very simple answers, like giving a single word. Some more required
a couple of sentences. Others needed much more research to answer them, and required
an essay to provide the answer. Now, how complex is the problem of cancer? Will
providing the answer require a single word, a single sentence, multiple sentences, a
short essay, or a freakin' book? Perhaps it could require a dozen freakin' books. Who
knows? Do you? Did Nixon? I know that I don't know. My specialty isn't biology,
medicine, etc.
I should bury you, but then people would not seeing my reply, and would not become
educated by it. - BoneheadFarker, on 11/19/2008, -0/+1"Type 2 Diabetes can promote similar symptoms to that of type II."
Yes, it does...almost identical symptoms... - ViscidGobs, on 04/24/2009, -0/+1This clinical trial is not for the cancer drug, however.
- ViscidGobs, on 04/24/2009, -0/+1My wife is type 1 and it believed that type one is closely related to MS. That the pancreatic islet cells become inflamed they aren't actually killed. The inflammation causes the islet cells to stop producing insulin. The whole key to therapy in the relative studies that are going on is to find treatments that either reduce the inflammation or bypass it.
- Grok22, on 11/19/2008, -0/+1I wish they would link to the original study
- dmcm, on 01/14/2009, -0/+1The Diabetes Library - Diabetes Drug Treatment pages at http://diabetes.boomja.com/Diabetes-Drug-Treatment ... is a wonderful resource with many links to Diabetes medicines.
- Odonthe1st, on 11/19/2008, -0/+1I'm hoping for some form of control put on the FDA and Imperial-pharma soon. The FDA is in the pocket of the industry it is supposed to police. I would welcome socialized medicine if it could put a stop to these evil people trying to capitalize on your fear. Look at Splenda- Sucralose (Splenda) is a chlorocarbon. The chlorocarbons have long been known for causing organ, genetic, and reproductive damage. It was fast tracked thorough testing in a few months and marketed heavily. And it's going to end up a worse situation then aspertame in my opinion. Just google "Splenda test" or something similar. Here's a link of an article about how bad splenda is: http://www.rense.com/general65/splend.htm
And cancer--The "American Cancer Society" is not a government organization, it's a private company of people trying to make money. They invest heavily in chemotherapy drugs, an 8+ billion dollar industry. So what treatment do you think the American Cancer Society is likely to recommend? Chemo is only useful in 20% of cancers but it is used in 95% of cancer treatment. "Just to make sure we're trying everything we can". Doctors that don't recommend standard treatments for cancer are fired from hospitals and eventually will have their license taken away. The best treatment for cancer can be found outside of the US. Chemo makes patients wish they were dead, it's that bad. How likely are you to survive cancer with no will to live? But it makes money. Richard Nixon declared a "War on Cancer" in something like 1977, why isn't it cured yet? Because the big money is in the treatment, not a cure.
I hope this drug isn't snatched up by the bastards in pharma and squashed so that they can continue selling their "treatments". Or maybe they can just make sure you need to take an expensive pill of it everyday for life so they can continue business as usual. -
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